DNA clue to life at high altitude
http://news.bbc.co.u...lth/8680503.stm
The ability of Tibetans to live on the "roof of the world" may be down to their DNA, US researchers say.
University of Utah researchers found 10 genes which help Tibetans thrive at heights where others get sick.
Two of the genes are linked to haemoglobin - the substance in blood that transports oxygen round the body.
Doctors say the research, published in Science, could lead to treatments for severe forms of altitude sickness and other illnesses.
Altitude sickness is the name given to ill-effects caused by the body's struggle to deal with a lack of oxygen at high altitude.
It can lead to brain and lung complications, which can threaten even the fittest mountaineers.
People native to high altitudes appear to be immune to such effects, through thousands of years of genetic selection.
Tibetans have evolved genes that others living at high altitudes - such as in the Andes - have not.
Professor Lynn Jorde, of the University of Utah School of Medicine, said: "For the first time, we have genes that explain that adaptation.
The ability of Tibetans to live on the "roof of the world" may be down to their DNA?
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Posted 14 May 2010 - 02:37 AM
I wonder if the same genes would make Tibetans sick when they are brought to low altitudes.University of Utah researchers found 10 genes which help Tibetans thrive at heights where others get sick.
That also made me wonder, whether the genes are that important in order for one to live in such a height?Tibetans have evolved genes that others living at high altitudes - such as in the Andes - have not.
Another people I can think of are the Tajiks in the Pamir highlands.
They also seem to be proud of their ability to tame Yaks.
Some guides say that it's not about the Physical strength.I've heard of friends saying that if you would like to travel to Tibet, it's best to be physically prepared as the high altitude is very challenging. You need to do a lot of physical exercise before going there.
I knew that it's caused by oxygen level, not lack of muscles.
I think one would have to rest (and eat?) until their level of haemoglobin is high enough.
Edited by qrasy, 14 May 2010 - 02:39 AM.
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Posted 15 May 2010 - 12:10 AM
I wonder if the same genes would make Tibetans sick when they are brought to low altitudes.
That also made me wonder, whether the genes are that important in order for one to live in such a height?
Another people I can think of are the Tajiks in the Pamir highlands.
They also seem to be proud of their ability to tame Yaks.
Some guides say that it's not about the Physical strength.
I knew that it's caused by oxygen level, not lack of muscles.
I think one would have to rest (and eat?) until their level of haemoglobin is high enough.
When your body is in top condition it operates more efficiently, and therefore each breathe you take is more efficient than if your body is out of shape.
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